Recombinant human tigit
Webb2 feb. 2024 · Alternatively, TIGIT was stimulated with Recombinant Human CD155 Fc Chimera Protein (R&D Systems, 9174-CD-050) plate-bound at 10 μg/ml. As isotype control, we used α-human IgG1 (MilliporeSigma, I5154-1MG). The FoxO1 inhibitor AS1842856 (EMD Millipore) was used at 25 nM, and the SHIP-1 inhibitor 3AC (Merck Millipore) was used at … WebbTIGIT; T cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; WUCAM Gene ID 201633 UniProt ID Q495A1 Product Notes This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including: • Increased sensitivity • Confirmed specificity • High repeatability • Excellent batch-to-batch consistency
Recombinant human tigit
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WebbRecombinant Active Human TIGIT Protein (Extracellular domain, 22-141) fused with a human IgG1 Fc tag at the C-terminus was expressed in HEK293. Description Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the … WebbThe mouse CD226-Fc and TIGIT-Fc recombinant proteins were custom-made by Chimerigen (Taizhou, China) and Novoprotein (CS15, Suzhou, China). 2.4 Cell culture In …
WebbTIGIT binds to CD112 (PVRL2/Nectin-2) and CD155 (PVR/Necl-5) that are expressed on dendritic cells (DC), endothelial cells, fibroblasts, and some tumor cells and can induce IL-10 release and inhibition of IL-12 production. ... Immunogen: Human TIGIT Recombinant Protein Application: Flow cytometry (Qualified) ... WebbWhen Recombinant Human CD155/PVR Fc Chimera (Catalog # 9174-CD ) is immobilized at 2.5 µg/mL (100 µL/well), Recombinant Human TIGIT (T103) His-tag binds with an ED 50 of 0.3-1.5 μg/mL. >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
WebbCompare TIGIT Protein LS-G142254 from LifeSpan BioSciences on Biocompare.com. Welcome Guest. Sign In Register. Products. Popular Categories; ... Purified recombinant protein of human T cell immunoreceptor with Ig and ITIM domains (TIGIT), with C-terminal DDK/His tag, expressed in human cells, 20 µ WebbConfocal immunofluorescent analysis of human CD8 + T cells using TIGIT (E5Y1W) XP ® Rabbit mAb (green) and CD8α (RPA-T8) Mouse mAb (FITC Conjugate) #55397 (red pseudocolor). Samples were mounted in ProLong ® Gold Antifade Reagent with DAPI #8961 (blue). CD8 + T cells were purified from human blood and stimulated for 7 days …
WebbRecombinant human TIGIT inhibitor antibody recognizing an epitope that prevents TIGIT interaction with CD155 on immune cells. Anti-TIGIT Antibody The store will not work correctly in the case when cookies are disabled.
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